Ca2+Mobilization Induced by Ouabain in Thymocytes Involves Intracellular and Extracellular Ca2+Pools
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Ca Mobilization Induced by Ouabain in Thymocytes Involves Intracellular and Extracellular Ca Pools
Immune dysfunction has been reported in hypertensive rats, and circulating levels of ouabain are increased in some experimental models of hypertension. Ouabain is an inhibitor of the Na /K -ATPase capable of diverse effects on cells of the immune system, but its mode of action on these cells is still unknown. The levels of cytoplasmic calcium ions play an important role in cell signaling, and o...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2003
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000072801.90600.c2